Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1261 | Obesity | ICEECE2012

Preclinical anti-obesity activity and safety assessment of a novel drug affecting CB1 receptor

Dugina J. , Kheifets I. , Bugaeva L. , Spasov A. , Vorobyova T. , Epstein O.

Dietressa is a novel drug for the treatment of obesity containing ultra low doses of antibodies to CB1 receptor. A number of new drugs are now at different stages of development, and cannabinoid receptor type 1 is one of the most challenging targets for obesity treatment. However, there are some safety concerns over CB1 receptor antagonists, especially their psychological adverse effects.The study included two parts: the first one was performed on 33 C57...